|英文名字||Rabbit MPO Polyclonal Antibody|
|产品描述||Myeloperoxidase is an important enzyme used by granulocytes during phagocytic lysis of foreign particles engulfed. In normal tissues and in a variety of myeloproliferative disorders myeloid cells of both neutrophilic and eosinophilic types, at all stages of maturation, exhibit strong cytoplasmic reactivity for MPO. Erythroid precursors, megakaryocytes, lymphoid cells, mast cells, and plasma cells are nonreactive. MPO is not observed in the neoplastic cells of a wide variety of epithelial tumors and sarcomas. MPO is useful in differentiating between myeloid and lymphoid leukemias.|
|背景||Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.|
|保存方法||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.|
Rabbit anti-MPO Polyclonal Antibody 相关文献：
Chrysin protects against renal ischemia reperfusion induced tubular cell apoptosis and inflammation in mice
白小姐精选玄机aMingwei Xu, Hongbo Shi, Dongcao Liu.
EXP THER MED白小姐精选玄机a. 2019 Jan 21 ; 2256- 2262.
Tisp40 deficiency limits renal inflammation and promotes tubular cell proliferation in renal ischemia reperfusion injury
Cong Qin, Ming Li, Tao Bai, Kang Yang, Tao Xu, Jie Zhang.
Exp Cell Res白小姐精选玄机a. 2018 Oct 01 ; 371 (1) : 255- 261.